KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TPP2
All Species:
28.18
Human Site:
S976
Identified Species:
47.69
UniProt:
P29144
Number Species:
13
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P29144
NP_003282.2
1249
138350
S976
L
A
G
S
L
T
L
S
K
T
E
L
G
K
K
Chimpanzee
Pan troglodytes
XP_001151602
1249
138350
S976
L
A
G
S
L
T
L
S
K
T
E
L
G
K
K
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
Cat
Felis silvestris
Mouse
Mus musculus
Q64514
1262
139860
S976
L
A
G
S
L
T
L
S
K
T
E
L
G
K
K
Rat
Rattus norvegicus
Q64560
1249
138274
S976
L
A
G
S
L
T
L
S
K
T
E
L
G
K
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001513544
1367
152093
S1081
L
A
G
S
L
T
L
S
K
T
E
L
G
K
K
Chicken
Gallus gallus
XP_425591
1248
138209
S975
L
A
G
A
L
T
L
S
K
T
E
L
G
K
K
Frog
Xenopus laevis
NP_001085380
1261
139671
S977
L
A
G
T
L
T
L
S
K
T
E
L
G
K
K
Zebra Danio
Brachydanio rerio
XP_693179
595
63935
E343
P
N
S
G
R
I
C
E
V
I
T
E
A
V
Q
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9V6K1
1441
158719
F1091
W
L
S
G
N
L
V
F
P
Q
D
E
V
G
R
Honey Bee
Apis mellifera
XP_395521
1450
161968
T984
S
G
S
Y
L
Q
G
T
L
T
F
C
K
D
D
Nematode Worm
Caenorhab. elegans
Q09541
1374
151070
F1032
G
S
F
L
A
G
T
F
S
A
L
K
D
S
D
Sea Urchin
Strong. purpuratus
XP_788834
1215
133209
G963
L
P
K
G
A
S
L
G
Q
I
L
T
G
Q
V
Poplar Tree
Populus trichocarpa
XP_002318216
1299
143140
G1017
L
L
G
S
I
S
Y
G
K
L
S
F
A
G
E
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_193817
1380
152349
L1096
G
E
I
S
Y
G
K
L
S
F
D
E
K
E
G
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.6
N.A.
N.A.
N.A.
95.3
96.8
N.A.
81.2
86
80.4
37.7
N.A.
34
41.3
35
54.7
Protein Similarity:
100
99.7
N.A.
N.A.
N.A.
97.4
98.7
N.A.
86.6
94.6
91.3
43.1
N.A.
53
59.2
53.4
71.6
P-Site Identity:
100
100
N.A.
N.A.
N.A.
100
100
N.A.
100
93.3
93.3
0
N.A.
0
13.3
0
20
P-Site Similarity:
100
100
N.A.
N.A.
N.A.
100
100
N.A.
100
100
100
6.6
N.A.
20
20
6.6
40
Percent
Protein Identity:
38
N.A.
N.A.
37.4
N.A.
N.A.
Protein Similarity:
56.9
N.A.
N.A.
54.1
N.A.
N.A.
P-Site Identity:
26.6
N.A.
N.A.
6.6
N.A.
N.A.
P-Site Similarity:
46.6
N.A.
N.A.
20
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
50
0
8
15
0
0
0
0
8
0
0
15
0
0
% A
% Cys:
0
0
0
0
0
0
8
0
0
0
0
8
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
15
0
8
8
15
% D
% Glu:
0
8
0
0
0
0
0
8
0
0
50
22
0
8
8
% E
% Phe:
0
0
8
0
0
0
0
15
0
8
8
8
0
0
0
% F
% Gly:
15
8
58
22
0
15
8
15
0
0
0
0
58
15
8
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
8
0
8
8
0
0
0
15
0
0
0
0
0
% I
% Lys:
0
0
8
0
0
0
8
0
58
0
0
8
15
50
50
% K
% Leu:
65
15
0
8
58
8
58
8
8
8
15
50
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
8
0
0
8
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
8
8
0
0
0
0
0
0
8
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
8
0
0
8
8
0
0
0
8
8
% Q
% Arg:
0
0
0
0
8
0
0
0
0
0
0
0
0
0
8
% R
% Ser:
8
8
22
50
0
15
0
50
15
0
8
0
0
8
0
% S
% Thr:
0
0
0
8
0
50
8
8
0
58
8
8
0
0
0
% T
% Val:
0
0
0
0
0
0
8
0
8
0
0
0
8
8
8
% V
% Trp:
8
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
8
8
0
8
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _